CQMED is interested in understanding how RNA binding proteins control gene expression at the RNA level in normal and disease conditions. The studies use CLIP-seq, RNA-seq, and bioinformatics to understand protein kinases that regulate RNA metabolisms such as microRNA control, alternative splicing, and protein translation. RNA metabolism is frequently perturbed in diseases such as polycystic kidney and lateral amyotrophic sclerosis. A set of kinases including SRPK2 (Serine arginine protein kinase), Bicc1 (bicaudal C homolog 1), and ASCC3 Activating Signal Cointegrator 1 Complex Subunit 3 are the focus of our projects.
27 de setembro de 2021CQMED lança vídeos sobre expressão e purificação de proteínas
12 de fevereiro de 2021Cientistas descobrem moléculas que desaceleram o desenvolvimento de câncer cerebral